Slice* Premix
Description: 0.2% emamectin medicated premix for inclusion into fish feed.
Active Ingredient: Emamectin benzoate
Formulation: 0.2% emamectin benzoate in an inert carrier.
Premix: Formula for SLICE* (Emamectin Benzoate 0.2% Aquaculture Premix)
| Components |
Percent (%w/w) |
| Emamectin Benzoate |
0.2 |
| Inert Ingredients |
99.8 |
Pharmacologic Properties: Emamectin is an avermectin compound derived synthetically from avermectins which are produced by fermentation of the soil organism Streptomyces avermitilis. The benzoate salt confers stability on the molecule. When fed to fish emamectin benzoate is absorbed from the gut and distributed to the tissue of the fish. When sea lice feed on tissues of treated fish, emamectin is taken up into the tissues of the louse. Emamectin then binds to ion channels of nerve cells and disrupts transmission of nerve impulses, which results in paralysis and death of the parasite. Emamectin benzoate is excreted slowly by fish and metabolized to inactive compounds, resulting in long-lasting protection. Target Species: Salmonids: including Atlantic salmon, Pacific salmon, brown trout, brook trout and rainbow trout.
Key Benefits
- High level efficacy: SLICE* rapidly killed all parasitic stages (motile and non-motile) of sea lice.
- Duration of efficacy: SLICE* killed all stages of sea lice including gravid adult females for up to 10 weeks.
- Efficacy unaffected by temperature: SLICE* was effective under a wide range of environmental conditions, i.e. water temperatures of 5o-15oC in both freshwater and seawater.
- Well tolerated: SLICE* was well tolerated at more than 3x the dose rate with no mortality or significant reduction in feeding associated with treatment.
- Well tolerated and effective: when administered to smolts prior to transfer to sea.
Label Indications: For the treatment and prevention of lice infestations in salmonids caused by Lepeophtheirus salmonis,
Caligus elongatus, Caligus teres and Caligus rogercressyi.
| Common name |
Fish Species |
Lice species |
| Atlantic salmon |
Salmo salar |
L. salmonis, Caligus spp. |
| Rainbow trout |
Oncorhynchus mykiss |
L. salmonis, Caligus spp. |
| Brown or sea trout |
Salmo trutta |
L. salmonis, Caligus spp. |
| Brook trout |
Salvelinus fontinalis |
Salmincola edwardsii |
SLICE* Clinical Trials:
Dosage and Administration: Medicated feed is prepared by coating SLICE* Premix onto the surface of non-medicated fish feed pellets.
Administer at 50μg/kg fish biomass/day for seven consecutive days. The suggested feeding rate is 0.5% fish biomass per day. This would require two 2.5 kg sachets of SLICE* Premix for each 1,000 kg of feed.
Withdrawal time: Approved species, claims and withdrawal times may vary from country to country. Please check your local package insert or contact your local Schering-Plough Animal Health representative for more details.
Product Presentation: SLICE* Premix is supplied in 2.5 kg sachets containing 5 g of emamectin benzoate (0.2% w/w)
Special Requirements: As designated by local regulatory authorities.
Storage Conditions: Store in a dry place. Between 2o and 30o C.
Shelf-life: Sachet - Emamectin Benzoate 0.2% Aquaculture Premix has a shelf life of 36 months Medicated feed - 6 months Target Diseases
This literature is intended for international use. Specific product details of indications, registration license status, and trademarks, etc. may vary from country to country. Users should check the license status, local label and/or data sheet for exact specifications of usage or contact the local Intervet/Schering-Plough Animal Health representative.* Trademark
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