Tribrissen* 40% Powder
Description: Trimethoprim and sulfadiazine powder, antibacterial
Active Ingredient: Trimethoprim and sulfadiazine
Formulation: Powder for incorporation into fish feed. Contains 66.7g trimethoprim /kg and 333.3g sulfadiazine /kg.
Pharmacologic Properties: Tribrissen is active against a wide spectrum of bacterial pathogens, both Gram-negative and Gram-positive. It is bactericidal against susceptible strains and is often effective against sulfonamide-resistant organisms.
Proven effective against the following pathogens:
- Vibrio anguillarum
- Eschericia coli
- Proteus species
- Pasteurella species
- Salmonella species
- Shigella species
- Streptococcus species
- Yersinia ruckeri
In vitro, sulfadiazine is usually only bacteriostatic. Tribrissen imposes a sequential double blockade on bacterial metabolism. This deprives bacteria of nucleic acids and proteins essential for survival and multiplication and produces a high level of antibacterial activity, which is usually bactericidal. Target Species: Salmonids: (salmon, trout, char), sea bass
Key Benefits:
- Sequential double-blockade effect created by combining trimethoprim and sulphadiazine markedly lowers the minimum inhibitory concentration (MIC) compared to that required of either of these components used separately.
- Many strains of bacteria that are not susceptible to either trimethoprim or sulphadiazine separately, are susceptible to Tribrissen*.
- Tribrissen* is also effective against sulfonamide-resistant organisms
Label Indications: For the treatment of infections caused by organisms susceptible to trimethoprim/sulfadiazine*. Dosage and Administration: The recommended dose is 30 mg of combined active ingredients (75mg powder) per kg bodyweight of fish daily for a period of 7-10 days. Tribrissen 40% powder is intended solely for administration in feed. It may be incorporated into the feed at time of manufacture or mixed with manufactured feed prior to feeding.
Withdrawal time: Approved species, claims and withdrawal times may vary from country to country. Please check your local package insert or contact your local Schering-Plough Animal Health representative for more details.
Product Presentation:
- 1kg polypropylene tub
- 3.75 kg tinplate container
- 20kg drum
Special Requirements for Use:
As designated by local regulatory authorities.
Storage Conditions: Store in original container in a dry place. Protect from light. Re-close partly used container.
Shelf-life: See local package insert for details.
**Approved species, claims and withdrawal times may vary from country to country. Please check your local package insert or contact your local Schering-Plough Animal Health representative for more details. Target Diseases
This literature is intended for international use. Specific product details of indications, registration license status, and trademarks, etc. may vary from country to country. Users should check the license status, local label and/or data sheet for exact specifications of usage or contact the local Intervet/Schering-Plough Animal Health representative.* Trademark
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